KARISMA® RHCOLLAGEN The First and Only Injectable RH Collagen The greatest invention for a clear face Home Page » Aging + Collagen — The anabolic processes of collagen undergo a slowdown directly proportional to aging — Fragmentation and disorientation of the fibers which increase in stiffness Collagen decreases in time For this reason we must induce Fibrobalsts to produce new Type I Collagen — Modifications of interactions and bonds existing between collagen subunits and between the fibers themselves (cross linking)